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Journal articles
Microwave spectroscopic detection of human Hsp70 protein on annealed gold nanostructures on ITO glass strips
Abstract : Conductive indium-tin oxide (ITO) and non-conductive glass substrates were successfully modified with embedded gold nanoparticles (AuNPs) formed by controlled thermal annealing at 550 °C for 8 h in a preselected oven. The authors characterized the formation of AuNPs using two microscopic techniques: scanning electron microscopy (SEM) and atomic force microscopy (AFM). The analytical performances of the nanostructured-glasses were compared regarding biosensing of Hsp70, an ATP-driven molecular chaperone. In this work, the human heat-shock protein (Hsp70), was chosen as a model biomarker of body stress disorders for microwave spectroscopic investigations. It was found that microwave screening at 4 GHz allowed for the first time the detection of 12 ng/µL/cm2 of Hsp70.
https://hal-utt.archives-ouvertes.fr/hal-02365657
Contributor : Rodica Elena Ionescu <>
Submitted on : Friday, November 15, 2019 - 2:42:53 PM
Last modification on : Monday, December 9, 2019 - 2:10:05 PM
Contributor : Rodica Elena Ionescu <>
Submitted on : Friday, November 15, 2019 - 2:42:53 PM
Last modification on : Monday, December 9, 2019 - 2:10:05 PM
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